Cloning and developmental expression of a novel, secreted frizzled-related protein from the sea urchin, Strongylocentrotus purpuratus

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Cloning and developmental expression of a novel, secreted frizzled-related protein from the sea urchin, Strongylocentrotus purpuratus

Wnt proteins and their receptors, members of the frizzled protein family, play a key role in regulating a wide range of developmental processes. Recently, putative regulators of Wnt signaling known as secreted frizzled-related proteins (SFRPs) have been identified in several vertebrates. Here, we describe the cloning of a novel SFRP (suSFRP1) from the sea urchin, Strongylocentrotus purpuratus. ...

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Quantitative developmental transcriptomes of the sea urchin Strongylocentrotus purpuratus.

Development depends on the precise control of gene expression in time and space. A critical step towards understanding the global gene regulatory networks underlying development is to obtain comprehensive information on gene expression. In this study, we measured expression profiles for the entire expressed gene set during sea urchin embryonic development. We confirmed the reliability of these ...

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The Genome of the Sea Urchin Strongylocentrotus purpuratus

References and Notes 1. C. Harrold, J. S. Pearse, Echinoderm Studies 2, 137 (1987). 2. L. Rogers-Bennett, in Edible Sea Urchins: Biology and Ecology, J. M. Lawrence, Ed. (Elsevier, Amsterdam, Netherlands, 2007), pp. 393–425. 3. P. K. Dayton et al., Ecol. Monogr. 62, 421 (1992). 4. A. W. Ebeling et al., Mar. Biol. 84, 287 (1985). 5. K. D. Lafferty, Ecol. Appl. 14, 1566 (2004). 6. J. S. Pearse, A...

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The Genome of the Sea Urchin Strongylocentrotus purpuratus

References and Notes 1. C. Harrold, J. S. Pearse, Echinoderm Studies 2, 137 (1987). 2. L. Rogers-Bennett, in Edible Sea Urchins: Biology and Ecology, J. M. Lawrence, Ed. (Elsevier, Amsterdam, Netherlands, 2007), pp. 393–425. 3. P. K. Dayton et al., Ecol. Monogr. 62, 421 (1992). 4. A. W. Ebeling et al., Mar. Biol. 84, 287 (1985). 5. K. D. Lafferty, Ecol. Appl. 14, 1566 (2004). 6. J. S. Pearse, A...

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The genome of the sea urchin Strongylocentrotus purpuratus.

We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The g...

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ژورنال

عنوان ژورنال: Mechanisms of Development

سال: 2002

ISSN: 0925-4773

DOI: 10.1016/s0925-4773(01)00657-8